Dexamethasone-d5

A deuterium-labelled analogue of the synthetic glucocorticoid dexamethasone, Dexamethasone-d5 carries five deuterium atoms in place of hydrogen and is widely used as an internal standard in quantitative residue analysis. Because the labelled compound behaves almost identically to the analyte during extraction and chromatography while remaining distinguishable by mass, it corrects for losses and ion suppression across sample preparation and detection. Applications include method development and validation for veterinary drug residues in animal-derived foods, isotope dilution calibration, and verification of instrument response stability across LC-MS/MS batch runs. The substance is a pale yellow solid with the formula C22H24D5FO5 and a molecular weight of 397.49. It should be kept at -20 °C ± 5 °C and transported with ice packs, and is offered in 1 mg, 10 mg, 25 mg, 50 mg and 100 mg pack sizes. Enquiries regarding availability, supporting documents or a quotation are welcome.
Pack sizes and lead time
| Pack size | Availability | Quote |
|---|---|---|
| 1 mg | In stock | |
| 10 mg | 35 days | |
| 25 mg | On request | |
| 50 mg | On request | |
| 100 mg | On request |
What the documents contain
- Certificate of analysis — issued per lot: catalogue and lot number, the value assigned to the material and the analytical basis for it.
- Safety data sheet — supplied for the catalogue item, and the basis for the transport classification used on the shipment.
- Storage and shipping conditions for this item: -20℃±5℃, Shipping with Ice Packs.
Frequently asked questions
Is a certificate of analysis (COA) available for Dexamethasone-d5?
Yes. A batch-specific COA and the MSDS are issued for every lot of Dexamethasone-d5 (catalogue number CCAD300748). Use the COA link on this page, or email chao.lu@cato-chem.com with the lot number printed on your label and we will send the matching document.
What pack sizes and lead times are offered?
Pack sizes 1 mg are held in stock and typically ship within 1–2 working days Other sizes (10 mg) are quoted with a lead time of approximately 35 days.
How is the purity of Dexamethasone-d5 documented?
Purity is determined per batch and stated on the COA together with the analytical data used for its assignment. If your method requires a specific grade or a particular pharmacopoeial naming, tell us the requirement when you enquire and we will confirm suitability.
Can you supply a larger quantity or a custom synthesis?
Yes. Quantities above the listed pack sizes are quoted on request, and custom synthesis or isolation from related starting materials can be discussed for compounds not held in stock. Contact chao.lu@cato-chem.com with the target quantity and required delivery date.
How is Dexamethasone-d5 shipped?
Shipping conditions for this item: Shipping with Ice Packs. Shipments are packed to maintain the specified storage condition, and the SDS is provided for transport classification.

