Tetrodotoxin

Tetrodotoxin is a naturally occurring marine biotoxin found in pufferfish and certain other aquatic species, acting as a selective blocker of voltage-gated sodium channels and associated with severe neurotoxic poisoning. It is monitored in seafood safety programmes and in clinical and forensic investigations, so a well-characterised reference standard is needed for reliable identification and measurement. Typical laboratory use includes LC-MS/MS method development and validation, construction of calibration curves at low concentrations, recovery and matrix-effect evaluation in fish tissue, and confirmation of suspect samples against an authenticated material. The compound corresponds to the formula C11H17N3O8 with a molecular weight of 319.27 and is a white powder. It should be stored at -20 °C ± 5 °C and shipped with ice packs, and is available in 1 mg and 10 mg pack sizes. Enquiries for supporting documentation or a quotation are welcome.
Pack sizes and lead time
| Pack size | Availability | Quote |
|---|---|---|
| 1 mg | In stock | |
| 10 mg | 10 days |
What the documents contain
- Certificate of analysis — issued per lot: catalogue and lot number, the value assigned to the material and the analytical basis for it.
- Safety data sheet — supplied for the catalogue item, and the basis for the transport classification used on the shipment.
- Storage and shipping conditions for this item: -20℃±5℃, Shipping with Ice Packs.
Frequently asked questions
Is a certificate of analysis (COA) available for Tetrodotoxin?
Yes. A batch-specific COA and the MSDS are issued for every lot of Tetrodotoxin (catalogue number CCHM700902). Use the COA link on this page, or email chao.lu@cato-chem.com with the lot number printed on your label and we will send the matching document.
What pack sizes and lead times are offered?
Pack sizes 1 mg are held in stock and typically ship within 1–2 working days Other sizes (10 mg) are quoted with a lead time of approximately 10 days.
How is the purity of Tetrodotoxin documented?
Purity is determined per batch and stated on the COA together with the analytical data used for its assignment. If your method requires a specific grade or a particular pharmacopoeial naming, tell us the requirement when you enquire and we will confirm suitability.
Can you supply a larger quantity or a custom synthesis?
Yes. Quantities above the listed pack sizes are quoted on request, and custom synthesis or isolation from related starting materials can be discussed for compounds not held in stock. Contact chao.lu@cato-chem.com with the target quantity and required delivery date.
How is Tetrodotoxin shipped?
Shipping conditions for this item: Shipping with Ice Packs. Shipments are packed to maintain the specified storage condition, and the SDS is provided for transport classification.



